Symbol
Name
ID

Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
MGI:97384

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased serum serotonin
Disease(s) Associated with NTRK2	Increased serum serotonin
autistic disorder

Mouse Phenotypes

homeostasis/metabolism phenotype

increased susceptibility to dopaminergic neuron neurotoxicity

abnormal circulating corticosterone level

decreased circulating corticosterone level

decreased circulating follicle stimulating hormone level

increased circulating insulin level

increased circulating leptin level

decreased circulating adrenocorticotropin level

increased circulating adrenocorticotropin level

increased circulating HDL cholesterol level

impaired glucose tolerance

abnormal lipid level

Availability

Mouse Genotype

Ntrk2^tm1Bxu/Ntrk2^tm1Bxu

Ntrk2^tm1Rohr/Ntrk2^tm1Rohr

Ntrk2^{tm1b(EUCOMM)Wtsi}/Ntrk2⁺

Ntrk2^tm1Mini/Ntrk2⁺

Ntrk2^tm1Rohr/Ntrk2⁺

Ntrk2^tm2Kln/Ntrk2^tm2Kln
Tg(Cck-cre,-lacZ)1Mini/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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