About Help FAQ

Symbol
Name
ID

Pnp
purine-nucleoside phosphorylase
MGI:97365

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased lymphocyte proliferation in response to mitogen	Abnormality of B cell physiology	Impaired T cell function
Disease(s) Associated with PNP
purine nucleoside phosphorylase deficiency

Mouse Phenotypes		increased cellular sensitivity to gamma-irradiation	increased thymocyte apoptosis	decreased B cell proliferation	abnormal DNA repair	abnormal mitochondrial physiology
Availability	Mouse Genotype	increased cellular sensitivity to gamma-irradiation	increased thymocyte apoptosis	decreased B cell proliferation	abnormal DNA repair	abnormal mitochondrial physiology
	Pnp^bata/Pnp^bata
	Pnp^tm1Cmr/Pnp^tm1Cmr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23