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Symbol
Name
ID
Notch1
notch 1
MGI:97363
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Ascites
Disease(s) Associated with NOTCH1
Adams-Oliver syndrome

Mouse Phenotypes
homeostasis/metabolism phenotype
hemopericardium
pericardial effusion
decreased susceptibility to diet-induced obesity
hyperglycemia
increased circulating insulin level
insulin resistance
Availability Mouse Genotype
Notch1tm1Agt/Notch1tm1Agt
Tg(Tek-cre)1Ywa/0  (conditional)
Notch1tm1Agt/Notch1tm1Agt
Tg(Tek-cre)12Flv/0  (conditional)
Notch1tm1Agt/Notch1tm1Agt
Tg(Wt1-cre)#Jbeb/0  (conditional)
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Wt1-cre)#Jbeb/0  (conditional)
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Neurog3-cre)C1Able/0  (conditional)
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Neurod1-cre)1Able/0  (conditional)
*
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Adipoq-cre)1Evdr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory