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Symbol
Name
ID
Notch1
notch 1
MGI:97363
Phenotype annotations related to embryo
Darker colors indicate more annotations
Human Phenotypes
Oligohydramnios
Disease(s) Associated with NOTCH1
Adams-Oliver syndrome

Mouse Phenotypes
abnormal placenta vasculature
abnormal placental labyrinth vasculature morphology
abnormal vitelline vasculature morphology
absent vitelline blood vessels
small pharyngeal arch
incomplete embryo turning
abnormal left-right axis symmetry of the somites
abnormal rostral-caudal axis patterning
embryonic growth arrest
embryonic growth retardation
decreased embryo size
abnormal embryonic tissue morphology
abnormal embryonic neuroepithelium morphology
kinked neural tube
neural tube degeneration
notochord degeneration
abnormal somite development
abnormal somite size
delayed somite formation
pale yolk sac
abnormal vitelline vascular remodeling
Availability Mouse Genotype
Notch1sot/Notch1sot
Notch1tm1Con/Notch1tm1Con
Notch1tm1Grid/Notch1tm1Grid
Notch1tm1Pst/Notch1tm1Pst
Notch1tm1Rko/Notch1tm1Rko
Notch1tm2.1Pst/Notch1tm2.1Pst
Notch1tm2Pst/Notch1tm2.1Pst
Notch1tm1Agt/Notch1tm1Agt
Tg(Tek-cre)1Ywa/0  (conditional)
Notch1tm1Agt/Notch1tm1Agt
Tg(Tek-cre)12Flv/0  (conditional)
Notch1tm2Rko/Notch1tm4(cre)Rko  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory