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Symbol
Name
ID
Nf2
neurofibromin 2
MGI:97307
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations
Human Phenotypes
Vestibular schwannoma
Bilateral vestibular schwannoma
Unilateral vestibular schwannoma
Vertigo
Sensorineural hearing impairment
Hearing impairment
Tinnitus
Disease(s) Associated with NF2
vestibular schwannomatosis

Mouse Phenotypes
abnormal auditory brainstem response waveform shape
increased or absent threshold for auditory brainstem response
sensorineural hearing loss
increased susceptibility to otitis media
Availability Mouse Genotype
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)1Brn/0  (conditional)
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0  (conditional)
Nf2tm2Gth/Nf2tm2Gth
Tg(Postn-cre)1Sjc/0  (conditional)
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory