Symbol Name ID |
Myc
myelocytomatosis oncogene MGI:97250 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Acute promyelocytic leukemia |
Burkitt lymphoma |
Neoplasm of the oral cavity |
Breast carcinoma |
Prostate cancer |
Bladder neoplasm |
Transitional cell carcinoma of the bladder |
Disease(s) Associated with MYC | |||||||
acute promyelocytic leukemia | |||||||
breast cancer | |||||||
Burkitt lymphoma | |||||||
prostate cancer | |||||||
urinary bladder cancer |
Mouse Phenotypes | neoplasm |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
increased pancreas tumor incidence |
increased pancreatic acinar cell carcinoma incidence |
increased pituitary gland tumor incidence |
increased T cell derived lymphoma incidence |
increased hepatocellular carcinoma incidence |
increased hepatoma incidence |
increased liver adenoma incidence |
increased metastatic potential |
increased adenoma incidence |
increased leukemia incidence |
increased lymphoma incidence |
increased B cell derived lymphoma incidence |
increased sarcoma incidence |
increased brain tumor incidence |
decreased tumor incidence |
increased tumor incidence |
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Availability | Mouse Genotype | |||||||||||||||||||
Bmyctm1Mpo/Bmyctm1Mpo | * | |||||||||||||||||||
Myctm1Jlc/Myctm1Jlc | ||||||||||||||||||||
Myctm1Lbox/Myctm1Lbox | ||||||||||||||||||||
Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp | ||||||||||||||||||||
Myctm1Lbox/Myc+ | ||||||||||||||||||||
Tg(Alb1-Myc)#Sst/0 | ||||||||||||||||||||
Tg(Ela1-Myc)158Bri/0 | ||||||||||||||||||||
Tg(Ela1-Myc)159Bri/0 | ||||||||||||||||||||
Tg(Ela1-Myc)160Bri/0 | ||||||||||||||||||||
Tg(HBB-Myc)#Cos/0 | ||||||||||||||||||||
Tg(HBVX*,-Myc)#Skp/0 | ||||||||||||||||||||
Tg(IghMyc)22Bri/0 | ||||||||||||||||||||
Tg(MMTV-Myc)141-3Led/0 | ||||||||||||||||||||
Tg(MMTV-Myc)WT13Jrn/0 | ||||||||||||||||||||
Tg(MMTV-Myc)WT21Jrn/0 | ||||||||||||||||||||
Tg(MMTV-Myc*T58A)TA14Jrn/0 | ||||||||||||||||||||
Tg(MMTV-Myc*T58A)TA39Jrn/0 | ||||||||||||||||||||
Tg(MMTV-Myc*T58A)TA41Jrn/0 | ||||||||||||||||||||
Tg(Pklr-Myc)73Ak/0 | ||||||||||||||||||||
Tg(Thy1-cmyc)6Kio/0 | ||||||||||||||||||||
Tg(Thy1-cmyc)6LKio/0 | ||||||||||||||||||||
Tg(WapMyc)212Bri/0 | ||||||||||||||||||||
Tg(IghMyc)22Bri/? | ||||||||||||||||||||
Gt(ROSA)26Sortm1(Myc)Rcse/Gt(ROSA)26Sortm1(Myc)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
* | |||||||||||||||||||
Gt(ROSA)26Sortm2(myc*T58A)Rcse/Gt(ROSA)26Sortm2(myc*T58A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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Gt(ROSA)26Sortm3(myc*S62A)Rcse/Gt(ROSA)26Sortm3(myc*S62A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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