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Symbol
Name
ID
Myc
myelocytomatosis oncogene
MGI:97250
Phenotype annotations related to neoplasm
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Acute promyelocytic leukemia
Burkitt lymphoma
Neoplasm of the oral cavity
Breast carcinoma
Prostate cancer
Bladder neoplasm
Transitional cell carcinoma of the bladder
Disease(s) Associated with MYC
acute promyelocytic leukemia
breast cancer
Burkitt lymphoma
prostate cancer
urinary bladder cancer

Mouse Phenotypes
neoplasm
increased mammary gland tumor incidence
increased mammary adenocarcinoma incidence
increased pancreas tumor incidence
increased pancreatic acinar cell carcinoma incidence
increased pituitary gland tumor incidence
increased T cell derived lymphoma incidence
increased hepatocellular carcinoma incidence
increased hepatoma incidence
increased liver adenoma incidence
increased metastatic potential
increased adenoma incidence
increased leukemia incidence
increased lymphoma incidence
increased B cell derived lymphoma incidence
increased sarcoma incidence
increased brain tumor incidence
decreased tumor incidence
increased tumor incidence
Availability Mouse Genotype
Bmyctm1Mpo/Bmyctm1Mpo *
Myctm1Jlc/Myctm1Jlc
Myctm1Lbox/Myctm1Lbox
Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp
Myctm1Lbox/Myc+
Tg(Alb1-Myc)#Sst/0
Tg(Ela1-Myc)158Bri/0
Tg(Ela1-Myc)159Bri/0
Tg(Ela1-Myc)160Bri/0
Tg(HBB-Myc)#Cos/0
Tg(HBVX*,-Myc)#Skp/0
Tg(IghMyc)22Bri/0
Tg(MMTV-Myc)141-3Led/0
Tg(MMTV-Myc)WT13Jrn/0
Tg(MMTV-Myc)WT21Jrn/0
Tg(MMTV-Myc*T58A)TA14Jrn/0
Tg(MMTV-Myc*T58A)TA39Jrn/0
Tg(MMTV-Myc*T58A)TA41Jrn/0
Tg(Pklr-Myc)73Ak/0
Tg(Thy1-cmyc)6Kio/0
Tg(Thy1-cmyc)6LKio/0
Tg(WapMyc)212Bri/0
Tg(IghMyc)22Bri/?
Gt(ROSA)26Sortm1(Myc)Rcse/Gt(ROSA)26Sortm1(Myc)Rcse
Tg(Wap-cre)11738Mam/0  (conditional)
*
Gt(ROSA)26Sortm2(myc*T58A)Rcse/Gt(ROSA)26Sortm2(myc*T58A)Rcse
Tg(Wap-cre)11738Mam/0  (conditional)
Gt(ROSA)26Sortm3(myc*S62A)Rcse/Gt(ROSA)26Sortm3(myc*S62A)Rcse
Tg(Wap-cre)11738Mam/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory