Symbol
Name
ID

Lrp1
low density lipoprotein receptor-related protein 1
MGI:96828

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

homeostasis/metabolism phenotype

abnormal vascular wound healing

decreased susceptibility to diet-induced obesity

impaired adaptive thermogenesis

abnormal blood homeostasis

decreased circulating glucose level

hypoglycemia

decreased circulating insulin level

decreased circulating leptin level

abnormal circulating lipid level

decreased circulating free fatty acids level

abnormal circulating protein level

increased circulating alkaline phosphatase level

increased circulating factor VIII level

increased circulating von Willebrand factor level

decreased body surface temperature

abnormal body temperature homeostasis

increased energy expenditure

increased oxygen consumption

abnormal glucose homeostasis

improved glucose tolerance

abnormal lipid homeostasis

decreased brain cholesterol level

abnormal lipid level

decreased liver triglyceride level

decreased triglyceride level

Availability

Mouse Genotype

Lrp1^{tm1.1(KOMP)Wtsi}/Lrp1⁺

Lrp1^tm2Her/Lrp1^tm2Her
Tg(Mx1-cre)29-4Her/0 (conditional)

Lrp1^tm2Her/Lrp1^tm2Her (conditional)

Lrp1^tm2Her/Lrp1^tm2Her
Tg(Syn1-cre)671Jxm/0 (conditional)

Lrp1^tm2Her/Lrp1^tm2Her
Tg(Fabp4-cre)1Rev/0 (conditional)

Lrp1^tm2Her/Lrp1^tm2Her
Tg(Tagln-cre)1Her/0 (conditional)

Lrp1^tm2Her/Lrp1^tm2Her
Tg(Camk2a-cre)T29-1Stl/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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