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Symbol
Name
ID

Lmna
lamin A
MGI:96794

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Abnormal lymphocyte physiology
Disease(s) Associated with LMNA	Abnormal lymphocyte physiology
dilated cardiomyopathy 1A

Mouse Phenotypes

abnormal fat cell differentiation

myocardium necrosis

cardiac interstitial fibrosis

azoospermia

oligozoospermia

abnormal cell nucleus morphology

aneuploidy

abnormal nuclear lamina morphology

increased middle ear goblet cell number

abnormal cell physiology

abnormal cell cycle

abnormal mitotic spindle assembly checkpoint

abnormal meiosis

abnormal chromosomal synapsis

abnormal female meiosis

arrest of male meiosis

abnormal mitosis

abnormal cell differentiation

decreased fibroblast proliferation

abnormal respiratory electron transport chain

abnormal mitochondrial ATP synthesis coupled electron transport

abnormal double-strand DNA break repair

abnormal DNA replication

Availability

Mouse Genotype

Lmna^Dhe/Lmna^Dhe

Lmna^{Gt(S7-1F1)Sor}/Lmna^{Gt(S7-1F1)Sor}

Lmna^tm1.1Otin/Lmna^tm1.1Otin

Lmna^tm1Gbon/Lmna^tm1Gbon

Lmna^tm1Lgf/Lmna^tm1Lgf

Lmna^tm1Rben/Lmna^tm1Rben

Lmna^tm1Stw/Lmna^tm1Stw

Lmna^tm2.1Gbon/Lmna^tm2.1Gbon

Lmna^tm2Stw/Lmna^tm2Stw

Lmna^tm3Lgf/Lmna^tm3Lgf

Lmna^tm3Stw/Lmna^tm3Stw

Lmna^tm5Lgf/Lmna^tm5Lgf

Lmna^tm6Lgf/Lmna^tm6Lgf

Lmna^tm7Lgf/Lmna^tm7Lgf

Lmna^tm8Lgf/Lmna^tm8Lgf

Lmna^Dhe/Lmna⁺

Lmna^em1Fenz/Lmna⁺

Lmna^tm1.1Otin/Lmna⁺

Lmna^tm1Lgf/Lmna⁺

Lmna^tm1Stw/Lmna⁺

Lmna^tm1Stw/Lmna^tm7Lgf

Lmna^tm2Lgf/Lmna^tm7Lgf

Lmna^tm4Lgf/Lmna⁺

Lmna^tm7Lgf/Lmna⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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