|
Symbol Name ID |
Ldlr
low density lipoprotein receptor MGI:96765 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased LDL cholesterol concentration |
| Disease(s) Associated with LDLR | |
| familial hypercholesterolemia |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
amyloid beta deposits |
abnormal circulating amino acid level |
increased circulating glucose level |
hyperglycemia |
decreased circulating corticosterone level |
increased circulating insulin level |
abnormal circulating cholesterol level |
decreased circulating HDL cholesterol level |
increased circulating HDL cholesterol level |
abnormal circulating LDL cholesterol level |
increased circulating LDL cholesterol level |
increased circulating VLDL cholesterol level |
increased circulating cholesterol level |
increased circulating free fatty acids level |
decreased circulating triglyceride level |
increased circulating triglyceride level |
increased circulating VLDL triglyceride level |
increased circulating iron level |
abnormal circulating protein level |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-10 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
increased circulating alanine transaminase level |
decreased circulating unsaturated transferrin level |
abnormal glucose homeostasis |
impaired glucose tolerance |
insulin resistance |
abnormal lipid homeostasis |
abnormal cholesterol homeostasis |
increased liver cholesterol level |
increased cholesterol level |
abnormal triglyceride level |
increased liver triglyceride level |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
| LdlrHlb301/LdlrHlb301 | * | |||||||||||||||||||||||||||||||||||
| Ldlrtm1b(EUCOMM)Wtsi/Ldlrtm1b(EUCOMM)Wtsi | ||||||||||||||||||||||||||||||||||||
| Ldlrtm1Her/Ldlrtm1Her | * | |||||||||||||||||||||||||||||||||||
| LdlrHlb301/Ldlr+ | * | |||||||||||||||||||||||||||||||||||
| LdlrRgsc366/Ldlr+ | ||||||||||||||||||||||||||||||||||||
| Ldlrtm1Her/Ldlr+ | ||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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