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Symbol
Name
ID
Krt10
keratin 10
MGI:96685
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Palmoplantar hyperkeratosis
Erythroderma
Abnormal blistering of the skin
Epidermal acanthosis
Scaling skin
Congenital bullous ichthyosiform erythroderma
Disease(s) Associated with KRT10
epidermolytic hyperkeratosis

Mouse Phenotypes
abnormal sebocyte morphology
abnormal sebocyte differentiation
enlarged sebaceous gland
abnormal sebaceous lipid secretion
increased sebum secretion
greasy coat
ruffled hair
waved hair
abnormal skin morphology
abnormal epidermal layer morphology
abnormal epidermis stratum basale morphology
abnormal epidermis stratum corneum morphology
abnormal stratum corneum lipid matrix formation
hyperkeratosis
abnormal epidermis stratum granulosum morphology
increased keratohyalin granule size
hypergranulosis
abnormal epidermis stratum spinosum morphology
acanthosis
abnormal epidermis suprabasal layer morphology
epidermal hyperplasia
blistering
flaky skin
reddish skin
scaly skin
skin lesions
translucent skin
increased sebocyte proliferation
decreased skin tensile strength
Availability Mouse Genotype
Krt10tm1Tmm/Krt10tm1Tmm
Krt10tm2Tmm/Krt10tm2Tmm
Krt10tm1Tmm/Krt10+
Krt10M1Btlr/?
Krt10tm1Der/Krt10tm1Der
Tg(KRT14-cre/PGR)1Der/0  (conditional)
Krt10tm1Der/Krt10+
Tg(KRT14-cre/PGR)1Der/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory