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Symbol
Name
ID
Itgb2
integrin beta 2
MGI:96611
Phenotype annotations related to integument
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Poor wound healing
Skin ulcer
Disease(s) Associated with ITGB2
leukocyte adhesion deficiency 1

Mouse Phenotypes
integument phenotype
dermatitis
alopecia
abnormal hair follicle dermal papilla morphology
abnormal dermal layer morphology
mixed cellular infiltration to dermis
abnormal epidermal layer morphology
hyperkeratosis
orthokeratosis
parakeratosis
acanthosis
epidermal hyperplasia
reddish skin
scaly skin
spontaneous skin ulceration
abnormal skin condition
psoriasis
Availability Mouse Genotype
Itgb2tm1Bay/Itgb2tm1Bay *! ! !
Itgb2tm2Bay/Itgb2tm2Bay *
Itgb2tm1Bay/Itgb2tm2Bay *! ! !

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory