Symbol
Name
ID

Irf1
interferon regulatory factor 1
MGI:96590

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased level of L-fucose in urine
Disease(s) Associated with IRF1	Increased level of L-fucose in urine
stomach cancer

Mouse Phenotypes

abnormal vascular wound healing

abnormal DNA repair

decreased circulating interferon-gamma level

increased circulating interferon-gamma level

abnormal circulating interleukin-10 level

increased circulating interleukin-13 level

decreased circulating interleukin-2 level

increased circulating interleukin-3 level

abnormal circulating interleukin-4 level

increased circulating interleukin-4 level

increased circulating interleukin-5 level

increased circulating interleukin-6 level

abnormal circulating alanine transaminase level

abnormal cytokine level

increased susceptibility to xenobiotic induced morbidity/mortality

increased incidence of tumors by chemical induction

Availability

Mouse Genotype

Irf1^tm1Cwe/Irf1^tm1Cwe

Irf1^tm1Mak/Irf1^tm1Mak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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