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interferon regulatory factor 1
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased level of L-fucose in urine
Disease(s) Associated with IRF1
stomach cancer

Mouse Phenotypes
abnormal vascular wound healing
abnormal DNA repair
decreased circulating interferon-gamma level
increased circulating interferon-gamma level
abnormal circulating interleukin-10 level
increased circulating interleukin-13 level
decreased circulating interleukin-2 level
increased circulating interleukin-3 level
abnormal circulating interleukin-4 level
increased circulating interleukin-4 level
increased circulating interleukin-5 level
increased circulating interleukin-6 level
abnormal circulating alanine transaminase level
abnormal cytokine level
increased sensitivity to xenobiotic induced morbidity/mortality
increased incidence of tumors by chemical induction
Availability Mouse Genotype

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory