|
Symbol Name ID |
Il6
interleukin 6 MGI:96559 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Anorexia |
Depression |
Personality changes |
Polydipsia |
Polyphagia |
Hyperactivity |
Fatigue |
| Disease(s) Associated with IL6 | |||||||
| Graves' disease | |||||||
| Huntington's disease | |||||||
| lymphoplasmacytic lymphoma | |||||||
| type 1 diabetes mellitus |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
enhanced behavioral response to morphine |
abnormal learning/memory/conditioning |
abnormal passive avoidance behavior |
abnormal inhibitory learning |
abnormal object recognition memory |
abnormal long-term object recognition memory |
impaired long-term object recognition memory |
abnormal spatial learning |
abnormal food intake |
abnormal emotion/affect behavior |
increased aggression towards male mice |
behavioral despair |
increased anxiety-related response |
increased fear-related response |
abnormal pilomotor reflex |
tremors |
ataxia |
hunched posture |
abnormal stationary movement |
abnormal head movements |
decreased locomotor activity |
increased locomotor activity |
paraparesis |
abnormal sleep pattern |
abnormal frequency of paradoxical sleep |
abnormal mechanical nociception |
decreased chemically-elicited antinociception |
abnormal social investigation |
seizures |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Il6tm1Kopf/Il6tm1Kopf | ||||||||||||||||||||||||||||||||
| Il6tm1Poli/Il6tm1Poli | * | |||||||||||||||||||||||||||||||
| Tg(Gfap-Il6)G167Lms/Tg(Gfap-Il6)G167Lms | ||||||||||||||||||||||||||||||||
| Tg(Gfap-Il6)G16Lms/0 Tg(Gfap-lacZ)1Lms/0 |
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| Tg(Gfap-Il6)G167Lms/0 | ||||||||||||||||||||||||||||||||
| Tg(Gfap-Il6)G369Lms/0 | ||||||||||||||||||||||||||||||||
| Il6tm1.1Jho/Il6tm1.1Jho Tg(GFAP-cre)8Gtm/0 (conditional) |
* | |||||||||||||||||||||||||||||||
| Il6tm1.1Jho/Il6+ Tg(GFAP-cre)8Gtm/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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