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Symbol
Name
ID
Il1rn
interleukin 1 receptor antagonist
MGI:96547
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Trismus
Macrocephaly
Camptodactyly of finger
Interphalangeal joint erosions
Clubbing of fingers
Swan neck-like deformities of the fingers
Dupuytren contracture
Limited elbow movement
Joint swelling
Limited shoulder movement
Joint stiffness
Stiff interphalangeal joints
Bone pain
Pathologic fracture
Vertebral compression fracture
Osteopenia
Osteoporosis
Arthritis
Rheumatoid arthritis
Polyarticular arthritis
Digital flexor tenosynovitis
Disease(s) Associated with IL1RN
graft-versus-host disease
Muckle-Wells syndrome
multiple myeloma
osteoporosis
rheumatoid arthritis
Sjogren's syndrome
systemic lupus erythematosus

Mouse Phenotypes
increased susceptibility to induced arthritis
rheumatoid arthritis
Availability Mouse Genotype
Il1rntm1Nick/Il1rntm1Nick
Il1rntm1Yiw/Il1rntm1Yiw
Il1rntm1.1Cga/Il1rntm1.1Cga
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory