Symbol
Name
ID

Htr2c
5-hydroxytryptamine (serotonin) receptor 2C
MGI:96281

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased waist to hip ratio	Obesity
Disease(s) Associated with HTR2C	Increased waist to hip ratio	Obesity
obesity

Mouse Phenotypes

decreased body fat mass

growth/size/body region phenotype

decreased body mass index

decreased lean body mass

decreased body weight

slow postnatal weight gain

increased body weight

decreased body length

increased susceptibility to age related obesity

increased susceptibility to diet-induced obesity

postnatal growth retardation

Availability

Mouse Genotype

Htr2c^tm1.1Eme/Htr2c^tm1.1Eme

Htr2c^tm1Knk/Htr2c^tm1Knk

Htr2c^tm2Knk/Htr2c^tm2Knk

Htr2c^tm1.1Eme/Htr2c⁺

Htr2c^tm1Knk/Htr2c⁺

Htr2c^tm1Knk/Htr2c^tm2Knk

Htr2c^tm1.1Eme/Y

Htr2c^tm1Jke/Y

Htr2c^tm1Jul/Y

Htr2c^tm1Knk/Y

Htr2c^tm2Knk/Y

Htr2c^tm2Jke/Htr2c^tm2Jke
Tg(Pomc1-cre)16Lowl/0 (conditional)

Htr2c^tm2Jke/Htr2c^tm2Jke
Tg(Pomc-cre/ERT2)#Jke/0 (conditional)

Htr2c^tm1Jke/Y
Tg(Pomc1-cre)16Lowl/0 (conditional)

Htr2c^tm2Jke/Y
Tg(Zp3-cre)93Knw/0 (conditional)

Htr2c^tm2Jke/Y
Tg(Pomc1-cre)16Lowl/0 (conditional)

Htr2c^tm2Jke/Y
Tg(Pomc-cre/ERT2)#Jke/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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