Symbol Name ID |
Hras
Harvey rat sarcoma virus oncogene MGI:96224 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Adenoma sebaceum |
Hemangioma |
Cavernous hemangioma |
Hepatocellular carcinoma |
Vestibular schwannoma |
Non-medullary thyroid carcinoma |
Papillary thyroid carcinoma |
Bladder neoplasm |
Bladder carcinoma |
Transitional cell carcinoma of the bladder |
Neoplasm of the skin |
Basal cell carcinoma |
Cutaneous melanoma |
Rhabdomyosarcoma |
Neoplasm |
Sarcoma |
Disease(s) Associated with HRAS | ||||||||||||||||
Costello syndrome | ||||||||||||||||
hepatocellular carcinoma | ||||||||||||||||
large congenital melanocytic nevus | ||||||||||||||||
linear nevus sebaceous syndrome | ||||||||||||||||
thyroid gland papillary carcinoma | ||||||||||||||||
urinary bladder cancer |
Mouse Phenotypes | neoplasm |
increased stomach tumor incidence |
increased mammary adenocarcinoma incidence |
decreased incidence of tumors by chemical induction |
increased skin papilloma incidence |
increased hemangiosarcoma incidence |
increased papilloma incidence |
increased astrocytoma incidence |
|
Availability | Mouse Genotype | ||||||||
Hrastm1Mok/Hrastm1Mok | |||||||||
Hrastm2Xbr/Hrastm2Xbr | * | ||||||||
Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu | |||||||||
Tg(GFAP-Hras1)2Agu/0 | |||||||||
Hrastm1Jaf/Hrastm1Jaf Tg(TPO-cre)1Shk/0 (conditional) |
* | ||||||||
Hrastm1Jaf/Hras+ Tg(CAG-cre)13Miya/0 (conditional) |
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Hrastm1Jaf/? Tg(TPO-cre)1Shk/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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