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Symbol Name ID |
Hras
Harvey rat sarcoma virus oncogene MGI:96224 |
| Darker colors indicate more annotations |
| Human Phenotypes | Frontal bossing |
Prominent occiput |
Biparietal narrowing |
Cranial asymmetry |
Plagiocephaly |
Micrognathia |
Prominence of the premaxilla |
Dandy-Walker malformation |
Macrocephaly |
Wide anterior fontanel |
Coarse facial features |
Facial asymmetry |
Round face |
Full cheeks |
Adenoma sebaceum |
Pointed chin |
Broad forehead |
Prominent forehead |
Everted lower lip vermilion |
Thick lower lip vermilion |
Deep philtrum |
Long philtrum |
High palate |
Macroglossia |
Open mouth |
Abnormal dental morphology |
Abnormality of dental color |
Anteverted nares |
Narrow nasal ridge |
Broad nasal tip |
Depressed nasal bridge |
Short nose |
Downslanted palpebral fissures |
Epicanthus |
Telecanthus |
Periorbital fullness |
| Disease(s) Associated with HRAS | ||||||||||||||||||||||||||||||||||||
| Costello syndrome | ||||||||||||||||||||||||||||||||||||
| large congenital melanocytic nevus | ||||||||||||||||||||||||||||||||||||
| linear nevus sebaceous syndrome |
| Mouse Phenotypes | abnormal cranium morphology |
abnormal frontal bone morphology |
abnormal tooth development |
abnormal ameloblast morphology |
abnormal ameloblast differentiation |
abnormal enamel mineralization |
abnormal cervical loop morphology |
abnormal stellate reticulum morphology |
abnormal stratum intermedium morphology |
abnormal enamel morphology |
abnormal enamel rod pattern |
absent enamel |
malocclusion |
short premaxilla |
short maxilla |
jaw cyst |
short zygomatic bone |
domed cranium |
abnormal facial morphology |
abnormal lip morphology |
choanal stenosis |
depressed nasal bridge |
short nasal bridge |
deviated nasal septum |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||
| Hrastm2Xbr/Hrastm2Xbr | |||||||||||||||||||||||||
| Hrastm1Jaf/Hras+ Tg(CAG-cre)13Miya/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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