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Symbol
Name
ID
Gstm1
glutathione S-transferase, mu 1
MGI:95860
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Polyclonal elevation of IgM
Decreased circulating antibody level
Paraproteinemia
Abnormality of chromosome stability
Chromosome breakage
Abnormal erythrocyte enzyme concentration or activity
Abnormality of metabolism/homeostasis
Hypercalcemia
Increased circulating iron concentration
Decreased level of 1,5 anhydroglucitol in serum
Hyperbilirubinemia
Increased LDL cholesterol concentration
Hypercholesterolemia
Hypertriglyceridemia
Elevated circulating creatinine concentration
Abnormal circulating porphyrin concentration
Elevated circulating C-reactive protein concentration
Increased circulating ferritin concentration
Decreased circulating hepcidin concentration
Hyperproteinemia
Abnormal circulating enzyme concentration or activity
Elevated circulating hepatic transaminase concentration
Elevated circulating alkaline phosphatase concentration
Reduced uroporphyrinogen decarboxylase activity
Elevated erythrocyte sedimentation rate
Hyperglycemia
Glucose intolerance
Diabetes mellitus
Type II diabetes mellitus
Impaired glucose tolerance
Insulin resistance
Elevated sweat chloride
Ketoacidosis
Dehydration
Joint swelling
Pleural effusion
Fever
Food intolerance
Abnormality of vitamin B12 metabolism
Increased fecal porphyrin
Elevated hepatic iron concentration
Hepatic steatosis
Hypercalciuria
Hematuria
Pyuria
Increased level of L-fucose in urine
Increased urinary porphobilinogen
Proteinuria
Porphyrinuria
Amyloidosis
Increased serum serotonin
Corneal scarring
Scarring
Cerebellar calcifications
Disease(s) Associated with GSTM1
atopic dermatitis
autistic disorder
coronary artery disease
cystic fibrosis
Fanconi anemia
graft-versus-host disease
Hodgkin's lymphoma
medulloblastoma
multiple myeloma
porphyria cutanea tarda
rheumatoid arthritis
stomach cancer
systemic lupus erythematosus
systemic scleroderma
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
decreased circulating glucose level
increased circulating phosphate level
increased dopamine level
increased serotonin level
abnormal physiological response to xenobiotic
abnormal xenobiotic pharmacokinetics
Availability Mouse Genotype
Gstm1tm1Gcw/Gstm1tm1Gcw
Gstm1tm1Kfuj/Gstm1tm1Kfuj
Gstm6tm1b(EUCOMM)Hmgu/Gstm6tm1b(EUCOMM)Hmgu

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory