Symbol
Name
ID

Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Attention deficit hyperactivity disorder	Behavioral abnormality
Disease(s) Associated with GRIN2A	Attention deficit hyperactivity disorder	Behavioral abnormality
Landau-Kleffner syndrome

Mouse Phenotypes

behavior/neurological phenotype

impaired contextual conditioning behavior

impaired cued conditioning behavior

abnormal long term object recognition memory

decreased exploration in new environment

abnormal spatial learning

abnormal spatial working memory

abnormal depression-related behavior

decreased anxiety-related response

increased startle reflex

impaired coordination

jumpy

decreased vertical activity

decreased chemical nociceptive threshold

decreased chemically-elicited antinociception

allodynia

decreased thermal nociceptive threshold

reduced kindling response

Availability

Mouse Genotype

Grin2a^tm1.1Jpleo/Grin2a^tm1.1Jpleo

Grin2a^tm1.1Nhk/Grin2a^tm1.1Nhk

Grin2a^tm1.1Ppao/Grin2a^tm1.1Ppao

Grin2a^tm1.1Tnkw/Grin2a^tm1.1Tnkw

Grin2a^tm1Mim/Grin2a^tm1Mim

Grin2a^tm1Nak/Grin2a^tm1Nak

Grin2a^tm1Rsp/Grin2a^tm1Rsp

Tg(Camk2a-Grin2a)1Jzt/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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