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Symbol Name ID |
Gba1
glucosylceramidase beta 1 MGI:95665 |
| Darker colors indicate more annotations |
| Human Phenotypes | Polyclonal elevation of IgM |
Increased circulating antibody level |
Decreased HDL cholesterol concentration |
Elevated circulating C-reactive protein concentration |
Increased circulating ferritin concentration |
Elevated circulating CCL18 level |
Decreased beta-glucocerebrosidase level |
Hydrops fetalis |
Nonimmune hydrops fetalis |
Fever |
Hematuria |
Proteinuria |
Aortic valve calcification |
Mitral valve calcification |
Calcification of the aorta |
Vascular calcification |
Ascites |
| Disease(s) Associated with GBA1 | |||||||||||||||||
| Gaucher's disease | |||||||||||||||||
| Gaucher's disease perinatal lethal | |||||||||||||||||
| Gaucher's disease type I | |||||||||||||||||
| Gaucher's disease type III | |||||||||||||||||
| Gaucher's disease type IIIC |
| Mouse Phenotypes | decreased circulating HDL cholesterol level |
decreased circulating cholesterol level |
abnormal circulating cytokine level |
abnormal circulating chemokine level |
increased circulating interferon-gamma level |
decreased circulating interleukin-1 alpha level |
decreased circulating interleukin-1 beta level |
increased circulating interleukin-10 level |
increased circulating interleukin-13 level |
increased circulating interleukin-2 level |
increased circulating interleukin-3 level |
decreased circulating interleukin-6 level |
increased circulating interleukin-9 level |
decreased circulating tumor necrosis factor level |
increased circulating alanine transaminase level |
increased circulating amylase level |
increased circulating aspartate transaminase level |
cyanosis |
dehydration |
abnormal lipid homeostasis |
abnormal enzyme/coenzyme activity |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Gba1tm1.1Eginn/Gba1tm1.1Eginn | ||||||||||||||||||||||
| Gba1tm1Nsb/Gba1tm1Nsb | ||||||||||||||||||||||
| Gba1tm1Rlp/Gba1tm1Rlp | ||||||||||||||||||||||
| Gba1tm2.1Eginn/Gba1tm2.1Eginn | ||||||||||||||||||||||
| Gba1tm2Rlp/Gba1tm2Rlp | ||||||||||||||||||||||
| Gba1em1(IMPC)H/Gba1+ | ||||||||||||||||||||||
| Gba1tm1.1Karl/Gba1+ | ||||||||||||||||||||||
| Gba1tm1.1Pmis/Gba1tm1.1Pmis Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Gba1tm1Karl/Gba1tm1Karl Tg(Nes-cre)1Kln/? (conditional) |
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| Gba1tm2Karl/Gba1tm2Karl Tg(KRT14-cre)8Brn/? (conditional) |
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| Gba1tm1.1Pmis/Gba1tm1.2Pmis Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Gba1tm1Clk/Gba1tm1.1Clk Tg(Tek-cre)12Flv/0 (conditional) |
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| Gba1tm1Clk/Gba1tm1.1Clk Tg(EIIa-cre)C5379Lmgd/0 (conditional) |
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| Gba1tm1Clk/Gba1tm1.1Clk Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Gba1tm1Karl/Gba1tm1.1Karl Tg(Mx1-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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