|
Symbol Name ID |
Gata3
GATA binding protein 3 MGI:95663 |
| Darker colors indicate more annotations |
| Human Phenotypes | Sensorineural hearing impairment |
Progressive sensorineural hearing impairment |
| Disease(s) Associated with GATA3 | ||
| hypoparathyroidism-deafness-renal disease syndrome |
| Mouse Phenotypes | abnormal middle ear ossicle morphology |
abnormal incus morphology |
abnormal malleus morphology |
abnormal gonial bone morphology |
abnormal stapes morphology |
inner ear cyst |
abnormal inner ear development |
delayed inner ear development |
abnormal otic vesicle development |
small otic vesicle |
abnormal inner ear morphology |
abnormal cochlea morphology |
abnormal cochlear sensory epithelium morphology |
abnormal cochlear hair cell morphology |
decreased cochlear hair cell number |
absent cochlear hair cells |
cochlear inner hair cell degeneration |
abnormal cochlear outer hair cell morphology |
cochlear outer hair cell degeneration |
cochlear hair cell degeneration |
abnormal organ of Corti morphology |
decreased organ of Corti supporting cell number |
pillar cell degeneration |
degeneration of organ of Corti supporting cells |
organ of Corti degeneration |
decreased cochlea coiling |
absent common crus |
abnormal crista ampullaris morphology |
absent semicircular canals |
absent utricle |
absent vestibular saccule |
abnormal endolymphatic duct morphology |
inner ear hypoplasia |
abnormal tympanic ring morphology |
increased or absent threshold for auditory brainstem response |
absent distortion product otoacoustic emissions |
sensorineural hearing loss |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
| Gata3tm1Gsv/Gata3tm1Gsv | ||||||||||||||||||||||||||||||||||||||
| Gata3tm2Gsv/Gata3tm2Gsv | ||||||||||||||||||||||||||||||||||||||
| Gata3tm1Gsv/Gata3+ | ||||||||||||||||||||||||||||||||||||||
| Gata3tm1.1Gan/Gata3tm1.1Gan Tg(Pax2-cre)1Akg/0 (conditional) |
||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools