Symbol
Name
ID

Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
MGI:95614

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Lack of spontaneous play	Impaired ability to form peer relationships	Autistic behavior	Autism	Addictive alcohol use	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
Disease(s) Associated with GABRA2	Lack of spontaneous play	Impaired ability to form peer relationships	Autistic behavior	Autism	Addictive alcohol use	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
alcohol dependence
autistic disorder
developmental and epileptic encephalopathy 78

Mouse Phenotypes

abnormal behavior

enhanced behavioral response to anesthetic

impaired behavioral response to xenobiotic

abnormal conditioned emotional response

enhanced contextual conditioning behavior

enhanced cued conditioning behavior

decreased exploration in new environment

increased anxiety-related response

increased thigmotaxis

limb grasping

increased grip strength

trunk curl

decreased locomotor activity

hyperactivity

decreased chemically-elicited antinociception

Availability

Mouse Genotype

Gabra2^em1(IMPC)H/Gabra2^em1(IMPC)H

Gabra2^tm1.1Dias/Gabra2^tm1.1Dias

Gabra2^tm1.1Geh/Gabra2^tm1.1Geh

Gabra2^tm1.1Uru/Gabra2^tm1.1Uru

Gabra2^tm1Dns/Gabra2^tm1Dns

Gabra2^tm1Uru/Gabra2^tm1Uru
Tg(Scn10a-cre)1Rkun/0 (conditional)

Gabra2^tm2.1Uru/Gabra2^tm2.1Uru
Tg(Scn10a-cre)1Rkun/0 (conditional)

Gabra2^tm1Uru/Gabra2^tm2.1Uru
Tg(Scn10a-cre)1Rkun/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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