Symbol
Name
ID

Fgfr2
fibroblast growth factor receptor 2
MGI:95523

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Redundant neck skin	Short neck	Rhizomelic arm shortening	Inguinal hernia	Umbilical hernia	Redundant umbilical skin	Growth abnormality	Short stature
Disease(s) Associated with FGFR2	Redundant neck skin	Short neck	Rhizomelic arm shortening	Inguinal hernia	Umbilical hernia	Redundant umbilical skin	Growth abnormality	Short stature
acrocephalosyndactylia
Beare-Stevenson cutis gyrata syndrome
craniosynostosis
Pfeiffer syndrome
Saethre-Chotzen syndrome

Mouse Phenotypes

long incisors

decreased molar number

arrest of tooth development

absent teeth

malocclusion

abnormal nasal bone morphology

short nasal bone

abnormal palatine bone horizontal plate morphology

abnormal nasal capsule morphology

abnormal palate development

abnormal palatal mesenchymal cell proliferation

abnormal secondary palate development

abnormal palatal shelf fusion at midline

palatal shelves fail to meet at midline

palatal shelf fusion with tongue or mandible

abnormal facial morphology

small face

midface hypoplasia

short face

abnormal midface morphology

abnormal palate morphology

decreased palatal length

absent palatal rugae

cleft secondary palate

cleft palate

abnormal tongue morphology

tongue ankylosis

abnormal nasal septum cartilage morphology

abnormal nasal gland morphology

abnormal lateral nasal gland morphology

thick nasal septum

short snout

abnormal head shape

shortened head

meteorism

embryonic growth retardation

decreased embryo size

growth/size/body region phenotype

decreased birth weight

decreased birth body size

decreased body weight

slow postnatal weight gain

inner ear cyst

epidermal cyst

abnormal head morphology

decreased body length

decreased body size

disproportionate dwarf

postnatal growth retardation

decreased fetal size

Availability

Mouse Genotype

Fgfr2^m1Sgg/Fgfr2^m1Sgg

Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn

Fgfr2^tm1Cxd/Fgfr2^tm1Cxd

Fgfr2^tm1Schl/Fgfr2^tm1Schl

Fgfr2^tm2Schl/Fgfr2^tm2Schl

Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni

Fgfr2^tm3Dsn/Fgfr2^tm3Dsn

Fgfr2^tm4Lni/Fgfr2^tm4Lni

Fgfr2^m1Sgg/Fgfr2⁺

Fgfr2^tm1.1Dor/Fgfr2^hob

Fgfr2^tm1Schl/Fgfr2⁺

Fgfr2^tm2.3Dsn/Fgfr2⁺

Fgfr2^tm3.1Cxd/Fgfr2⁺

Fgfr2^tm3Ewj/Fgfr2⁺

Fgfr2^tm4Lni/Fgfr2⁺

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(Mnx1-cre)1Jrs/? (conditional)

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(Sftpc-cre)1Blh/0 (conditional)

Fgfr2^tm1Dsn/Fgfr2^tm1Dsn
Tg(KRT5-cre)5132Jlj/0 (conditional)

Fgfr2^tm1Dor/Fgfr2^tm1.1Dor
Twist2^tm1(cre)Dor/Twist2⁺ (conditional)

Fgfr2^tm1Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Cxd/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm3Cxd/Fgfr2⁺
Tg(Col2a1-cre)1Xya/0 (conditional)

Fgfr2^tm3Cxd/Fgfr2⁺
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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