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Symbol
Name
ID 		Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
MGI:95413
Phenotype annotations related to neoplasm
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Acute lymphoblastic leukemia
Ph-positive acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Acute myeloid leukemia
Chronic myelogenous leukemia
Myeloproliferative disorder
Lymphoma
Multiple myeloma
Myelodysplasia
Breast carcinoma
Colon cancer
Stomach cancer
Neoplasm of the liver
Hepatocellular carcinoma
Pancreatic adenocarcinoma
Neoplasm of the eye
Prostate cancer
Ovarian carcinoma
Bladder neoplasm
Transitional cell carcinoma of the bladder
Basal cell carcinoma
Papilloma
Squamous cell carcinoma
Neoplasm
Melanoma
Disease(s) Associated with ERCC2
acute lymphoblastic leukemia
acute myeloid leukemia
breast cancer
chronic myeloid leukemia
hepatocellular carcinoma
multiple myeloma
myelodysplastic syndrome
pancreatic cancer
photosensitive trichothiodystrophy 1
prostate cancer
stomach cancer
urinary bladder cancer
xeroderma pigmentosum
xeroderma pigmentosum group D

Mouse Phenotypes
neoplasm
increased incidence of tumors by chemical induction
increased skin tumor incidence
increased incidence of induced tumors
increased incidence of tumors by UV-induction
decreased tumor latency
Availability Mouse Genotype
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh *
Ercc2tm3Jhjh/Ercc2tm3Jhjh
Ercc2tm1Jhjh/Ercc2tm2(ERCC2)Jhjh
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory