|
Symbol Name ID |
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1 MGI:95412 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Hypercalcemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Elevated circulating hepatic transaminase concentration |
Abnormal circulating lactate dehydrogenase concentration |
Increased circulating lactate dehydrogenase concentration |
Elevated circulating alkaline phosphatase concentration |
Diabetes mellitus |
Joint swelling |
Pleural effusion |
Fever |
Abnormality of vitamin B12 metabolism |
Increased level of L-fucose in urine |
Amyloidosis |
| Disease(s) Associated with ERCC1 | ||||||||||||||||||
| multiple myeloma | ||||||||||||||||||
| osteosarcoma | ||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||
| stomach cancer |
| Mouse Phenotypes | abnormal DNA repair |
decreased circulating glucose level |
decreased circulating insulin level |
decreased circulating insulin-like growth factor I level |
increased circulating lactate level |
increased liver triglyceride level |
acidosis |
increased urine protein level |
increased susceptibility to xenobiotic induced morbidity/mortality |
increased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||||||||
| Ercc1tm1Dwm/Ercc1tm1Dwm Tg(Ttr-Ercc1)17Dwm/0 |
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| Ercc1tm1Jhjh/Ercc1tm1Jhjh | |||||||||||
| Ercc1tm2Jhjh/Ercc1tm2Jhjh | |||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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