Symbol
Name
ID

Dmd
dystrophin, muscular dystrophy
MGI:94909

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Elevated circulating creatine kinase concentration	Elevated circulating hepatic transaminase concentration	Abnormal urinary color	Myoglobinuria	Exercise intolerance
Disease(s) Associated with DMD	Elevated circulating creatine kinase concentration	Elevated circulating hepatic transaminase concentration	Abnormal urinary color	Myoglobinuria	Exercise intolerance
Becker muscular dystrophy
Duchenne muscular dystrophy

Mouse Phenotypes

homeostasis/metabolism phenotype

impaired exercise endurance

decreased aerobic running capacity

increased circulating alanine transaminase level

increased circulating alkaline phosphatase level

increased circulating aspartate transaminase level

increased circulating creatine kinase level

abnormal circulating pyruvate kinase level

increased circulating serum albumin level

increased circulating total protein level

increased creatine kinase level

increased growth hormone level

increased transforming growth factor beta level

increased creatine kinase activity

decreased physiological sensitivity to xenobiotic

Availability

Mouse Genotype

Dmd^{em1(IMPC)Hmgu}/Dmd^{em1(IMPC)Hmgu}

Dmd^em4Eno/Dmd^em4Eno

Dmd^mdx/Dmd^mdx

Dmd^mdx/Dmd⁺

Dmd^{em1(IMPC)Hmgu}/Y

Dmd^em1Eno/Y

Dmd^em4Eno/Y

Dmd^em#Tve/Y

Dmd^mdx/Y

Dmd^tm1Kmf/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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