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Symbol
Name
ID
Ager
advanced glycosylation end product-specific receptor
MGI:893592
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased level of 1,5 anhydroglucitol in serum
Increased LDL cholesterol concentration
Hypercholesterolemia
Hypertriglyceridemia
Elevated circulating hepatic transaminase concentration
Hyperglycemia
Glucose intolerance
Diabetes mellitus
Type II diabetes mellitus
Impaired glucose tolerance
Insulin resistance
Elevated sweat chloride
Ketoacidosis
Dehydration
Fever
Hypercalciuria
Hematuria
Pyuria
Proteinuria
Disease(s) Associated with AGER
coronary artery disease
cystic fibrosis
systemic lupus erythematosus
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
abnormal vascular wound healing
abnormal blood homeostasis
increased circulating glucose level
decreased circulating interleukin-6 level
Availability Mouse Genotype
Agertm1.1Arnd/Agertm1.1Arnd
Agertm1.1Hyam/Agertm1.1Hyam
Tg(Tagln-Ager)#Yon/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory