Symbol Name ID |
Tcof1
treacle ribosome biogenesis factor 1 MGI:892003 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Micrognathia |
Malar flattening |
Disease(s) Associated with TCOF1 | ||
Treacher Collins syndrome 1 |
Mouse Phenotypes | skeleton phenotype |
abnormal craniofacial bone morphology |
abnormal cranium morphology |
abnormal neurocranium morphology |
abnormal frontal bone morphology |
absent frontal bone |
frontal bone hypoplasia |
absent interparietal bone |
absent parietal bone |
abnormal temporal bone morphology |
temporal bone hypoplasia |
abnormal zygomatic arch morphology |
zygomatic arch hypoplasia |
small orbits |
abnormal viscerocranium morphology |
small mandible |
mandible hypoplasia |
short mandible |
abnormal maxilla morphology |
abnormal premaxilla morphology |
premaxilla hypoplasia |
short premaxilla |
maxilla hypoplasia |
short maxilla |
retrognathia |
abnormal nasal bone morphology |
nasal bone hypoplasia |
abnormal palatine bone morphology |
palatine bone hypoplasia |
absent turbinates |
facial bone hypoplasia |
acrania |
domed cranium |
abnormal middle ear ossicle morphology |
middle ear ossicle hypoplasia |
abnormal nasal capsule morphology |
rib fusion |
vertebral fusion |
delayed endochondral bone ossification |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
Tcof1tm1Mjd/Tcof1+ | *! | ! | ! | ! | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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