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Symbol
Name
ID
Cyp11b1
cytochrome P450, family 11, subfamily b, polypeptide 1
MGI:88583
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Abnormality of metabolism/homeostasis
Hypokalemia
Hypoglycemia
Hypokalemic alkalosis
Fever
Recurrent fever
Renal salt wasting
Increased circulating cortisol level
Disease(s) Associated with CYP11B1
congenital adrenal hyperplasia

Mouse Phenotypes
decreased circulating corticosterone level
increased circulating corticosterone level
decreased circulating insulin level
decreased circulating aldosterone level
increased circulating adrenocorticotropin level
hypokalemia
increased circulating potassium level
decreased circulating renin level
increased circulating renin level
abnormal enzyme/coenzyme level
impaired glucose tolerance
decreased urine aldosterone level
decreased urine corticosterone level
increased urine progesterone level
decreased circulating chloride level
increased urine deoxycorticosterone level
decreased urine osmolality
increased urine osmolality
abnormal enzyme/coenzyme activity
increased renin activity
abnormal response/metabolism to endogenous compounds
Availability Mouse Genotype
Cyp11b1tm1Chjk/Cyp11b1tm1Chjk
Cyp11b2tm1Hsk/Cyp11b2tm1Hsk
Cyp11b2tm2Hsk/Cyp11b2tm2Hsk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory