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Symbol
Name
ID

Ctsl
cathepsin L
MGI:88564

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

integument phenotype

increased keratinocyte proliferation

enlarged sebaceous gland

folliculitis

dermatitis

abnormal coat/ hair morphology

abnormal coat appearance

abnormal hair growth

alopecia

delayed hair appearance

focal dorsal hair loss

short hair

sparse hair

rough coat

greasy coat

abnormal hair shaft morphology

abnormal hair follicle morphology

abnormal hair follicle development

underdeveloped hair follicles

abnormal hair follicle orientation

hair follicle outer root sheath hyperplasia

dilated piliary canal

absent vibrissae

short vibrissae

sparse vibrissae

abnormal hair cycle

abnormal hair cycle catagen phase

thick dermal layer

abnormal epidermis stratum basale morphology

hyperkeratosis

orthokeratosis

hypergranulosis

acanthosis

epidermal hyperplasia

thick epidermis

scaly skin

shiny skin

skin lesions

thick skin

abnormal keratinocyte physiology

Availability

Mouse Genotype

Ctsl^fs/Ctsl^fs

Ctsl^m1Btlr/Ctsl^m1Btlr

Ctsl^nkt/Ctsl^nkt

*

Ctsl^tm1.1Thre/Ctsl^tm1.1Thre

Ctsl^tm1.2Thre/Ctsl^tm1.2Thre

Ctsl^tm1Alpk/Ctsl^tm1Alpk

!

Ctsl^tm1Cptr/Ctsl^tm1Cptr

Ctsl^tm1.2Thre/Ctsl⁺

*

Ctsl^tm1Alpk/Ctsl⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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