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Symbol
Name
ID
Crh
corticotropin releasing hormone
MGI:88496
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased susceptibility to neuronal excitotoxicity
abnormal homeostasis
increased circulating creatinine level
abnormal blood homeostasis
increased blood uric acid level
abnormal circulating glucose level
hyperglycemia
abnormal circulating hormone level
abnormal circulating adrenaline level
decreased circulating adrenaline level
increased circulating glucagon level
abnormal circulating corticosterone level
decreased circulating corticosterone level
increased circulating corticosterone level
increased circulating insulin level
decreased circulating leptin level
increased circulating leptin level
abnormal circulating noradrenaline level
abnormal circulating osteocalcin level
decreased circulating parathyroid hormone level
decreased circulating adrenocorticotropin level
increased circulating cholesterol level
increased circulating triglyceride level
increased circulating calcium level
increased circulating interleukin-6 level
increased circulating alanine transaminase level
increased circulating alkaline phosphatase level
increased circulating aspartate transaminase level
increased circulating total protein level
abnormal glucose homeostasis
impaired glucose tolerance
increased urine glucose level
insulin resistance
abnormal corticosterone level
increased urine corticosterone level
abnormal adrenocorticotropin level
abnormal urine homeostasis
increased urine calcium level
increased urine protein level
Availability Mouse Genotype
Crhtm1Maj/Crhtm1Maj
Crhtm2.2Maj/Crhtm2.2Maj
Crhm1H/Crh+ *
Crhtm2.1Maj/Crhtm2.1Maj
Tg(Sim1-cre)1Lowl/?  (conditional)
Gt(ROSA)26Sortm1(Crh)Jde/Gt(ROSA)26Sortm1(Crh)Jde
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/19/2018
MGI 6.12
The Jackson Laboratory