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Symbol
Name
ID

Col8a2
collagen, type VIII, alpha 2
MGI:88464

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Corneal stromal edema

Abnormal corneal endothelium morphology

Abnormal Descemet membrane morphology

Corneal guttata

Descemet Membrane Folds

Reduced number of corneal endothelial cells

Keratitis

Corneal degeneration

Corneal dystrophy

Corneal opacity

Nyctalopia

Visual impairment

Reduced visual acuity

Visual loss

Eye movement-induced pain

Disease(s) Associated with COL8A2

Fuchs' endothelial dystrophy

posterior polymorphous corneal dystrophy 2

Mouse Phenotypes		vision/eye phenotype	abnormal eye morphology	abnormal Descemet membrane morphology	decreased Descemet membrane thickness	abnormal cornea endothelium morphology	abnormal cornea epithelium morphology	decreased cornea thickness	decreased cornea stroma thickness	abnormal eye anterior chamber morphology	enlarged eye anterior chamber
Availability	Mouse Genotype	vision/eye phenotype	abnormal eye morphology	abnormal Descemet membrane morphology	decreased Descemet membrane thickness	abnormal cornea endothelium morphology	abnormal cornea epithelium morphology	decreased cornea thickness	decreased cornea stroma thickness	abnormal eye anterior chamber morphology	enlarged eye anterior chamber
	Col8a2^Aca23/Col8a2^Aca23	*
	Col8a2^tm1.1Asj/Col8a2^tm1.1Asj
	Col8a2^tm1Bjro/Col8a2^tm1Bjro
	Col8a2^tm2.1Asj/Col8a2^tm2.1Asj
	Col8a2^Aca23/Col8a2⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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