Symbol
Name
ID

Cftr
cystic fibrosis transmembrane conductance regulator
MGI:88388

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Polyclonal elevation of IgM

Hypoalbuminemia

Elevated circulating hepatic transaminase concentration

Elevated alkaline phosphatase of hepatic origin

Diabetes mellitus

Type I diabetes mellitus

Elevated sweat chloride

Dehydration

Pleural effusion

Fever

Reduced circulating vitamin A concentration

Decreased circulating vitamin E concentration

Decreased circulating vitamin D concentration

Decreased circulating vitamin K concentration

Hypercalciuria

Ascites

Disease(s) Associated with CFTR

bronchiectasis

cystic fibrosis

pancreatic cancer

primary sclerosing cholangitis

Mouse Phenotypes		homeostasis/metabolism phenotype	abnormal fluid regulation	abnormal ion homeostasis	abnormal phospholipid level	decreased physiological sensitivity to xenobiotic
Availability	Mouse Genotype	homeostasis/metabolism phenotype	abnormal fluid regulation	abnormal ion homeostasis	abnormal phospholipid level	decreased physiological sensitivity to xenobiotic
	Cftr^tm1.1Sdw/Cftr^tm1.1Sdw
	Cftr^tm1Kth/Cftr^tm1Kth	*
	Cftr^tm1Unc/Cftr^tm1Unc	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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