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Symbol
Name
ID
Cftr
cystic fibrosis transmembrane conductance regulator
MGI:88388
Phenotype annotations related to growth/size/body
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Hepatosplenomegaly
Ascites
Hepatomegaly
Peritoneal abscess
Decreased body mass index
Failure to thrive
Weight loss
Cachexia
Disease(s) Associated with CFTR
bronchiectasis
cystic fibrosis
pancreatic cancer
primary sclerosing cholangitis

Mouse Phenotypes
abnormal nasal mucosa morphology
abnormal paranasal sinus morphology
enlarged gallbladder
decreased body weight
weight loss
decreased body length
decreased body size
postnatal growth retardation
distended abdomen
spleen hyperplasia
Availability Mouse Genotype
Cftrem3Cwr/Cftrem3Cwr
Cftrtm1.1Cwr/Cftrtm1.1Cwr
Cftrtm1Cam/Cftrtm1Cam
Cftrtm1Eur/Cftrtm1Eur
Cftrtm1Hsc/Cftrtm1Hsc
Cftrtm1Kth/Cftrtm1Kth
Cftrtm1Unc/Cftrtm1Unc !
Cftrtm2Mrc/Cftrtm2Mrc
Cftrtm3Bay/Cftrtm3Bay
Cftrtm3Hgu/Cftrtm3Hgu
Cftrtm3Mrc/Cftrtm3Mrc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory