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Symbol Name ID |
Braf
Braf transforming gene MGI:88190 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Breast carcinoma |
Cavernous hemangioma |
Hereditary nonpolyposis colorectal carcinoma |
Colon cancer |
Neoplasm of the stomach |
Neoplasm of the liver |
Pancreatic adenocarcinoma |
Non-medullary thyroid carcinoma |
Papillary thyroid carcinoma |
Ovarian carcinoma |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Lentigo maligna melanoma |
Melanoma |
| Disease(s) Associated with BRAF | |||||||||||||||
| cardiofaciocutaneous syndrome | |||||||||||||||
| cardiofaciocutaneous syndrome 1 | |||||||||||||||
| colorectal cancer | |||||||||||||||
| Noonan syndrome 7 | |||||||||||||||
| pancreatic cancer | |||||||||||||||
| thyroid gland papillary carcinoma |
| Mouse Phenotypes | neoplasm |
increased gastrointestinal tumor incidence |
increased intestinal adenoma incidence |
increased gland tumor incidence |
increased pheochromocytoma incidence |
increased thyroid tumor incidence |
increased thyroid carcinoma incidence |
increased skin tumor incidence |
increased skin papilloma incidence |
increased metastatic potential |
increased lung adenoma incidence |
increased leukemia incidence |
increased carcinoma incidence |
increased lung adenocarcinoma incidence |
increased melanoma incidence |
increased lung tumor incidence |
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| Availability | Mouse Genotype | ||||||||||||||||
| Braftm1Bbd/Braf+ | |||||||||||||||||
| Braftm1Cpri/Braftm1Cpri Tg(Tyr-cre/ERT2)1Lru/0 (conditional) |
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| Braftm1Cpri/Braftm1Cpri Tg(TPO-cre)1Shk/0 (conditional) |
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| Braftm1.1Brd/Braf+ Tg(Vil1-cre)997Gum/0 (conditional) |
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| Braftm1Cpri/Braf+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Braftm1Cpri/Braf+ (conditional) | |||||||||||||||||
| Braftm1Mmcm/Braf+ (conditional) | |||||||||||||||||
| Braftm1Mmcm/Braf+ Polr2atm1(cre/ERT2)Bbd/Polr2a+ (conditional) |
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| Braftm1Mmcm/Braf+ Tg(Tg-cre/ERT2)#Mmcm/0 (conditional) |
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| Braftm1Mmcm/Braf+ Tg(TPO-cre/ERT2)1139Tyj/0 (conditional) |
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| Braftm1Mmcm/Braf+ Tg(Tyr-cre/ERT2)13Bos/0 (conditional) |
* | ||||||||||||||||
| Braftm1Rima/Braf+ Tg(Tyr-cre/ERT2)1Lru/0 (conditional) |
* | ||||||||||||||||
| Braftm2Cpri/Braf+ Tg(CMV-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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