Symbol Name ID |
Braf
Braf transforming gene MGI:88190 |
Darker colors indicate more annotations |
Human Phenotypes | Low posterior hairline |
Frontal bossing |
Biparietal narrowing |
Dolichocephaly |
Micrognathia |
Hypoplasia of the zygomatic bone |
Macrocephaly |
Relative macrocephaly |
Coarse facial features |
Long face |
Full cheeks |
Abnormality of the chin |
High forehead |
Narrow forehead |
Prominent forehead |
Deep philtrum |
Long philtrum |
Thick vermilion border |
Submucous cleft hard palate |
High palate |
Open mouth |
Abnormality of the dentition |
Dental malocclusion |
Open bite |
Anteverted nares |
Bulbous nose |
Depressed nasal bridge |
Short nose |
Aplasia/Hypoplasia of the eyebrow |
Absent eyebrow |
Abnormal eyelash morphology |
Sparse or absent eyelashes |
Absent eyelashes |
Long palpebral fissure |
Downslanted palpebral fissures |
Epicanthus |
Palpebral thickening |
Underdeveloped supraorbital ridges |
Disease(s) Associated with BRAF | ||||||||||||||||||||||||||||||||||||||
cardiofaciocutaneous syndrome | ||||||||||||||||||||||||||||||||||||||
cardiofaciocutaneous syndrome 1 | ||||||||||||||||||||||||||||||||||||||
Noonan syndrome 7 | ||||||||||||||||||||||||||||||||||||||
Noonan syndrome with multiple lentigines 3 |
Mouse Phenotypes | abnormal basicranium morphology |
decreased cranium length |
abnormal neurocranium morphology |
abnormal frontal bone morphology |
abnormal parietal bone morphology |
long incisors |
mandible hypoplasia |
abnormal facial morphology |
round head |
shortened head |
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Availability | Mouse Genotype | ||||||||||
Braftm1Bbd/Braf+ | |||||||||||
Braftm1Tumg/Braf+ Tg(CAG-cre)2Osb/0 (conditional) |
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Braftm2Cpri/Braf+ Tg(CMV-cre)1Cgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/12/2024 MGI 6.23 |
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