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Symbol
Name
ID

App
amyloid beta precursor protein
MGI:88059

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased circulating GABA concentration	Cerebral amyloid angiopathy
Disease(s) Associated with APP	Decreased circulating GABA concentration	Cerebral amyloid angiopathy
Alzheimer's disease 1
APP-related cerebral amyloid angiopathy

Mouse Phenotypes		homeostasis/metabolism phenotype	amyloidosis	amyloid beta deposits	increased blood urea nitrogen level	increased circulating calcium level	increased susceptibility to induced thrombosis
Availability	Mouse Genotype	homeostasis/metabolism phenotype	amyloidosis	amyloid beta deposits	increased blood urea nitrogen level	increased circulating calcium level	increased susceptibility to induced thrombosis
	App^tm1.1Tcs/App^tm1.1Tcs	*
	App^tm1.1Wevn/App^tm1.1Wevn
	App^tm1Dbo/App^tm1Dbo
	App^tm2.1Tcs/App^tm2.1Tcs
	App^tm3.1Tcs/App^tm3.1Tcs
	App^{tm1b(KOMP)Wtsi}/App⁺
	App^tm1Ini/App⁺
	Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)18Dbo/0
	Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)107Dbo/0
	Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)Dbo/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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