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Symbol
Name
ID
Adrb2
adrenergic receptor, beta 2
MGI:87938
Phenotype annotations related to vision/eye
Darker colors indicate more annotations
Human Phenotypes
Corneal arcus
Increased cup-to-disc ratio
Proptosis
Ocular hypertension
Myopia
Diplopia
Constriction of peripheral visual field
Glaucomatous visual field defect
Open angle glaucoma
Ptosis
Disease(s) Associated with ADRB2
familial hypercholesterolemia
Graves' disease
myasthenia gravis
open-angle glaucoma
primary open angle glaucoma

Mouse Phenotypes
increased retina apoptosis
abnormal Muller cell morphology
decreased retina ganglion cell number
abnormal eye morphology
abnormal retina morphology
abnormal retina ganglion layer morphology
abnormal electroretinogram waveform feature
decreased a-wave amplitude
decreased b-wave amplitude
Availability Mouse Genotype
Adrb2em1(IMPC)Mbp/Adrb2em1(IMPC)Mbp
Adrb2tm1Bkk/Adrb2tm1Bkk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory