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Symbol Name ID |
Iqsec2
IQ motif and Sec7 domain 2 MGI:3528396 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | No social interaction |
Autistic behavior |
Aggressive behavior |
| Disease(s) Associated with IQSEC2 | |||
| non-syndromic X-linked intellectual disability 1 |
| Mouse Phenotypes | behavior/neurological phenotype |
decreased susceptibility to pharmacologically induced seizures |
increased exploration in new environment |
impaired spatial learning |
abnormal spatial working memory |
increased anxiety-related response |
abnormal response to novelty |
abnormal response to social novelty |
decreased grip strength |
increased locomotor activity |
abnormal sexual interaction |
social withdrawal |
decreased vocalization |
decreased susceptibility to induction of seizure by inducing agent |
convulsive seizures |
sporadic seizures |
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| Availability | Mouse Genotype | ||||||||||||||||
| Iqsec2em1Alev/Iqsec2em1Alev | * | ||||||||||||||||
| Iqsec2em1Csbg/Iqsec2+ | |||||||||||||||||
| Iqsec2em1Frk/Iqsec2+ | |||||||||||||||||
| Iqsec2em1Csbg/Y | |||||||||||||||||
| Iqsec2em1Frk/Y | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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