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Symbol Name ID |
Grhl3
grainyhead like transcription factor 3 MGI:2655333 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | integument phenotype |
abnormal keratinocyte differentiation |
increased keratinocyte proliferation |
impaired skin barrier function |
abnormal skin morphology |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
abnormal epidermis stratum corneum morphology |
abnormal corneocyte morphology |
abnormal corneocyte envelope morphology |
abnormal epidermis stratum granulosum morphology |
thick epidermis stratum spinosum |
epidermal hyperplasia |
thick epidermis |
increased skin papilloma incidence |
increased skin squamous cell carcinoma incidence |
abnormal skin physiology |
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| Availability | Mouse Genotype | |||||||||||||||||
| Grhl3tm1Bogi/Grhl3tm1Bogi | ||||||||||||||||||
| Grhl3tm1Jane/Grhl3tm1Jane | ||||||||||||||||||
| Grhl3tm1Jane/Grhl3tm3.1Jane Tg(KRT14-cre)8Brn/0 (conditional) |
* | |||||||||||||||||
| Grhl3tm1Jane/Grhl3tm3.1Jane Tg(MMTV-cre)4Mam/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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