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Symbol
Name
ID

Lrrc8a
leucine rich repeat containing 8A VRAC subunit A
MGI:2652847

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Agammaglobulinemia
Disease(s) Associated with LRRC8A	Agammaglobulinemia
agammaglobulinemia 5

Mouse Phenotypes		homeostasis/metabolism phenotype	increased susceptibility to diet-induced obesity	increased energy expenditure	edema	impaired glucose tolerance	insulin resistance
Availability	Mouse Genotype	homeostasis/metabolism phenotype	increased susceptibility to diet-induced obesity	increased energy expenditure	edema	impaired glucose tolerance	insulin resistance
	Lrrc8a^{tm1.1(KOMP)Vlcg}/Lrrc8a^{tm1.1(KOMP)Vlcg}
	Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha	*
	Lrrc8a^em1Uia/Lrrc8a^em1Uia Tg(Adipoq-cre)1Evdr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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