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Symbol
Name
ID
Tph2
tryptophan hydroxylase 2
MGI:2651811
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Attention deficit hyperactivity disorder
Disease(s) Associated with TPH2
attention deficit hyperactivity disorder

Mouse Phenotypes
behavior/neurological phenotype
abnormal emotion/affect behavior
increased aggression
increased aggression towards females
increased aggression towards males
decreased coping response
increased anxiety-related response
abnormal response to novel object
weakness
induced hyperactivity
abnormal sleep pattern
abnormal maternal nurturing
abnormal pup retrieval
pup cannibalization
abnormal mating preference
Availability Mouse Genotype
Tph2tm1.1Zfc/Tph2tm1.1Zfc
Tph2tm1Bdr/Tph2tm1Bdr
Tph2tm1Lex/Tph2tm1Lex
Tph2tm1Mca/Tph2tm1Mca
Tph2tm1Pasq/Tph2tm1Pasq *
Tph2tm1Mca/Tph2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory