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Symbol
Name
ID
Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
MGI:2443241
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased activity of mitochondrial complex I
Abnormal mitochondria in muscle tissue
Increased serum pyruvate
Increased CSF lactate
Hypoglycemia
Diabetes mellitus
Increased circulating lactate concentration
Lactic acidosis
Metabolic acidosis
Disease(s) Associated with NDUFS1
mitochondrial complex I deficiency
nuclear type mitochondrial complex I deficiency 5

Mouse Phenotypes
increased circulating creatinine level
decreased circulating triglyceride level
increased circulating calcium level
increased circulating phosphate level
increased circulating sodium level
increased circulating lipase level
Availability Mouse Genotype
Ndufs1tm1b(EUCOMM)Hmgu/Ndufs1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory