Symbol Name ID |
Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1 MGI:2443241 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased activity of mitochondrial complex I |
Abnormal mitochondria in muscle tissue |
Increased serum pyruvate |
Increased CSF lactate |
Hypoglycemia |
Diabetes mellitus |
Increased circulating lactate concentration |
Lactic acidosis |
Metabolic acidosis |
Disease(s) Associated with NDUFS1 | |||||||||
mitochondrial complex I deficiency | |||||||||
nuclear type mitochondrial complex I deficiency 5 |
Mouse Phenotypes | increased circulating creatinine level |
decreased circulating triglyceride level |
increased circulating calcium level |
increased circulating phosphate level |
increased circulating sodium level |
increased circulating lipase level |
|
Availability | Mouse Genotype | ||||||
Ndufs1tm1b(EUCOMM)Hmgu/Ndufs1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|