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Symbol
Name
ID

Slc30a8
solute carrier family 30 (zinc transporter), member 8
MGI:2442682

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Type II diabetes mellitus	Insulin resistance
Disease(s) Associated with SLC30A8	Type II diabetes mellitus	Insulin resistance
type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	decreased insulin secretion	increased insulin secretion	increased susceptibility to diet-induced obesity	increased circulating glucose level	decreased circulating insulin level	increased circulating aspartate transaminase level	impaired glucose tolerance	abnormal insulin clearance	abnormal zinc homeostasis
Availability	Mouse Genotype	homeostasis/metabolism phenotype	decreased insulin secretion	increased insulin secretion	increased susceptibility to diet-induced obesity	increased circulating glucose level	decreased circulating insulin level	increased circulating aspartate transaminase level	impaired glucose tolerance	abnormal insulin clearance	abnormal zinc homeostasis
	Slc30a8^tm1.1Geno/Slc30a8^tm1.1Geno
	Slc30a8^{tm1a(KOMP)Wtsi}/Slc30a8^{tm1a(KOMP)Wtsi}
	Slc30a8^tm1Lex/Slc30a8^tm1Lex	*
	Slc30a8^tm1.1Htwt/Slc30a8^tm1.1Htwt Tg(Ins2-cre)25Mgn/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23