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Symbol
Name
ID
Tbc1d4
TBC1 domain family, member 4
MGI:2429660
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Insulin resistance
Disease(s) Associated with TBC1D4
acanthosis nigricans

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased circulating glucose level
decreased circulating insulin level
increased circulating free fatty acids level
increased circulating sodium level
decreased energy expenditure
decreased oxygen consumption
abnormal glucose homeostasis
abnormal gluconeogenesis
impaired glucose tolerance
abnormal glycogen homeostasis
insulin resistance
decreased adiponectin level
decreased circulating chloride level
decreased basal metabolism
Availability Mouse Genotype
Tbc1d4tm1.1Arte/Tbc1d4tm1.1Arte *
Tbc1d4tm1.2Arte/Tbc1d4tm1.2Arte
Tbc1d4tm1b(EUCOMM)Hmgu/Tbc1d4tm1b(EUCOMM)Hmgu
Tbc1d4tm1Lex/Tbc1d4tm1Lex

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory