About Help FAQ

Symbol
Name
ID

Tardbp
TAR DNA binding protein
MGI:2387629

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Foot dorsiflexor weakness

Lower limb muscle weakness

Upper limb muscle weakness

Gastroparesis

Rigidity

Spasticity

Muscle spasm

Muscle weakness

Fatigable weakness of bulbar muscles

Fatigable weakness of swallowing muscles

Fatigable weakness of respiratory muscles

Generalized muscle weakness

Respiratory insufficiency due to muscle weakness

Skeletal muscle atrophy

Progressive distal muscular atrophy

Progressive spinal muscular atrophy

Disease(s) Associated with TARDBP

amyotrophic lateral sclerosis

amyotrophic lateral sclerosis type 10

Parkinson's disease

Mouse Phenotypes		skeletal muscle fiber necrosis	abnormal muscle morphology	skeletal muscle atrophy	muscle degeneration	muscular atrophy	impaired muscle relaxation	abnormal muscle tone	muscle weakness	progressive muscle weakness
Availability	Mouse Genotype	skeletal muscle fiber necrosis	abnormal muscle morphology	skeletal muscle atrophy	muscle degeneration	muscular atrophy	impaired muscle relaxation	abnormal muscle tone	muscle weakness	progressive muscle weakness
	Tardbp^m1H/Tardbp⁺
	Tardbp^tm3.1Ckjs/Tardbp⁺
	Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu/0
	Tardbp^tm1.1Sobue/Tardbp^tm1.1Sobue Tg(SLC18A3-cre)Misa/0 (conditional)
	Mnx1^tm4(cre)Tmj/Mnx1⁺ Tardbp^tm1.1Ckjs/Tardbp^tm1.2Cjks (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23