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Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to integument
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Pilomatrixoma
Basal cell carcinoma
Disease(s) Associated with DICER1
multinodular goiter

Mouse Phenotypes
integument phenotype
abnormal coat/ hair morphology
abnormal hair growth
alopecia
delayed hair appearance
progressive hair loss
waved hair
abnormal hair shaft morphology
abnormal hair follicle morphology
small hair follicle bulb
abnormal hair follicle development
abnormal hair follicle inner root sheath morphology
abnormal hair follicle orientation
abnormal hair follicle bulge morphology
decreased hair follicle number
hair follicle degeneration
small hair follicles
abnormal vibrissa morphology
loss of vibrissae
abnormal hair cycle catagen phase
abnormal hair follicle regression
decreased hair follicle cell proliferation
abnormal epidermal layer morphology
epidermal hyperplasia
thick epidermis
abnormal skin appearance
dry skin
scaly skin
epidermal cyst
abnormal skin physiology
Availability Mouse Genotype
Dicer1tm1Smr/Dicer1tm1Smr
Tg(KRT14-cre)52Smr/0  (conditional)
Dicer1tm1Smr/Dicer1tm1Smr
Tg(KRT5-rtTA)1Glk/0
Tg(tetO-cre)1Jaw/0  (conditional)
*
Dicer1tm1Snj/Dicer1tm1Snj
Tg(KRT5-cre/PGR)1Der/0  (conditional)
Dicer1tm1Tara/Dicer1tm1Tara
Tg(KRT14-cre)1Efu/?  (conditional)
Dicer1tm1Tara/Dicer1tm1Tara
Tg(KRT14-cre)1Efu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory