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Symbol
Name
ID
Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
increased cardiomyocyte apoptosis
abnormal renal tubule epithelial cell primary cilium morphology
abnormal oocyte morphology
azoospermia
oligozoospermia
abnormal male germ cell morphology
abnormal spermatid morphology
decreased male germ cell number
abnormal cell physiology
abnormal DNA replication
abnormal mitosis
increased T cell apoptosis
increased kidney apoptosis
abnormal male germ cell apoptosis
increased apoptosis
abnormal granulocyte differentiation
abnormal megakaryocyte differentiation
decreased T cell proliferation
increased kidney cell proliferation
increased mesenchymal cell proliferation involved in lung development
decreased cell proliferation
early cellular replicative senescence
Availability Mouse Genotype
Dicer1tm1Bdh/Dicer1tm1Bdh
Plekha5Tg(AMH-cre)1Flor/0  (conditional)
Defb41tm1(icre)Psip/Defb41+
Dicer1tm1Bdh/Dicer1tm1Bdh  (conditional)
Dicer1tm1Dli/Dicer1tm1Dli
Tg(Cd4-cre)1Cwi/?  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Shhtm1(EGFP/cre)Cjt/Shh+  (conditional)
Dicer1tm1Smr/Dicer1tm1Smr
Tg(KRT5-rtTA)1Glk/0
Tg(tetO-cre)1Jaw/0  (conditional)
Dicer1tm1Smr/Dicer1tm1Smr
Pax8tm1.1(cre)Mbu/Pax8+  (conditional)
Dicer1tm1Smr/Dicer1tm1Smr
Tg(Myh6-cre)2182Mds/0  (conditional)
Dicer1tm1Snj/Dicer1tm1Snj  (conditional)
Dicer1tm1Tara/Dicer1tm1Tara
Tg(KRT14-cre)1Efu/?  (conditional)
Alpltm1(cre)Nagy/Alpl+
Dicer1tm1.1Mnn/Dicer1tm1.2Mnn  (conditional)
Dicer1tm1.1Mnn/Dicer1tm1.2Mnn
Tg(Zp3-cre)93Knw/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory