About Help FAQ

Symbol
Name
ID

Pnpla3
patatin-like phospholipase domain containing 3
MGI:2151796

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased LDL cholesterol concentration	Hypercholesterolemia	Hypertriglyceridemia	Glucose intolerance	Diabetes mellitus	Type II diabetes mellitus	Impaired glucose tolerance	Insulin resistance	Hepatic steatosis
Disease(s) Associated with PNPLA3	Increased LDL cholesterol concentration	Hypercholesterolemia	Hypertriglyceridemia	Glucose intolerance	Diabetes mellitus	Type II diabetes mellitus	Impaired glucose tolerance	Insulin resistance	Hepatic steatosis
coronary artery disease
metabolic dysfunction-associated steatotic liver disease
type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	increased fatty acids level	increased liver triglyceride level
Availability	Mouse Genotype	homeostasis/metabolism phenotype	increased fatty acids level	increased liver triglyceride level
	Pnpla3^tm1.1Hobb/Pnpla3^tm1.1Hobb
	Pnpla3^tm1Eek/Pnpla3^tm1Eek	*
	Pnpla3^tm2.1Hobb/Pnpla3^tm2.1Hobb
	Pnpla3^tm1.1Hobb/Pnpla3⁺	*
	Pnpla3^tm2.1Hobb/Pnpla3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23