Symbol
Name
ID

Kiss1r
KISS1 receptor
MGI:2148793

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased circulating follicle stimulating hormone concentration	Elevated circulating follicle stimulating hormone level	Decreased circulating luteinizing hormone level	Elevated circulating luteinizing hormone level
Disease(s) Associated with KISS1R		Elevated circulating follicle stimulating hormone level	Decreased circulating luteinizing hormone level	Elevated circulating luteinizing hormone level
central precocious puberty 1
hypogonadotropic hypogonadism 8 with or without anosmia

Mouse Phenotypes

homeostasis/metabolism phenotype

increased circulating creatinine level

abnormal blood homeostasis

increased blood urea nitrogen level

increased circulating glucose level

decreased circulating testosterone level

decreased circulating estradiol level

decreased circulating gonadotropin level

decreased circulating follicle stimulating hormone level

decreased circulating luteinizing hormone level

decreased circulating cholesterol level

decreased circulating triglyceride level

increased circulating alkaline phosphatase level

increased circulating serum albumin level

decreased circulating total protein level

abnormal follicle stimulating hormone level

abnormal luteinizing hormone level

decreased luteinizing hormone level

abnormal response/metabolism to endogenous compounds

Availability

Mouse Genotype

Kiss1r^Gt1Stei/Kiss1r^Gt1Stei

Kiss1r^{tm1.1(KOMP)Vlcg}/Kiss1r^{tm1.1(KOMP)Vlcg}

Kiss1r^tm1.1Lex/Kiss1r^tm1.1Lex

Kiss1r^tm1Coll/Kiss1r^tm1Coll

Kiss1r^tm1Rla/Kiss1r^tm1Rla

Kiss1r^tm1.1Aeh/Kiss1r^tm1.1Aeh
Tg(Gnrh1-cre)1Dlc/0 (conditional)

Kiss1r^tm1.1Aeh/Kiss1r^tm1.1Aeh
Tg(Gnrh1-cre)1Dlc/0
Tg(Gnrh1-Kiss1r)#Aeh/0 (conditional)

Kiss1r^tm1.1Hjn/Kiss1r^tm1.1Hjn
Tg(Gnrh1-cre)35Awo/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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